论文标题:老年性白内障的危险因素研究
The Study on Dangerous Factors of Senile Cataract
论文作者 马德环
论文导师 叶冬青;陈逖,论文学位 硕士,论文专业 流行病与卫生统计学
论文单位 安徽医科大学,点击次数 767,论文页数 55页File Size2034k
2001-05-24论文网 http://www.lw23.com/lunwen_1068847/ 白内障,危险因素,病例对照研究,条件Logistic回归
Cataract,Risk factors,Case-control study,Conditional Logistic regression
目的 探讨可能引起老年性白内障的危险因素，为制定预防白内障提供依据。方法 采用1:1病例对照研究方法对合肥市及定远县50对老年性白内障及对照进行问卷调查。研究因素采用条件Logistic回归单因素和多因素分析。结果 单因素分析结果发现白内障与居住环境、文化程度、吸烟、饮酒、血压、胆固醇、紫外线、腹泻及某些药物等多因素关系密切。其中居住在农村及小城市、高中及中专文化程度、吸烟、饮酒、高血压及紫外线、腹泻引起营养不良及类固醇等药可能是白内障发病的危险因素（OR均大于1）。维生素、阿斯匹林及谷光甘肽可能是保护因子（OR均小于1）。条件Logistic回归逐步法进行分析进一步证明了上述分析结果。结论 老年性白内障的发病与多种因素有关。合肥市和定远县两地白内障发病的危险因素基本具有其它地区人群共同的特点外，还有有别与其它地区人种的自身特点。
Objective This study armed at exploring the risk factors for cataract.Methods A 1:1 matched case-control study with 50 pairs on risk factors of cataract was carried out in Hefei city and Dingyuan county. The available data were analyzed by univariate and multivariate Logistic regression model.Results single factor analysis show: there are some relations to senile cataract and educational level environment smoking drinking hypertension ultraviolet ray cholesterol diarrhea and some medicine. Among the factors, that living in middle city and small town, high middle school and polytechnic school, smoking, drinking, hypertension, cholesterol, untraviolet ray, diarrhea and steroid et al may be risk factors. Furthermore results of Logistic stepwise regression analysis conformation this.Conclusions It suggest that senile cataract may correlate to education, smoking, drinking, hypertension, cholesterol, ultraviolet ray, diarrhea and some medicine. The risk factors of cataract in Anhui Hefei city and Dingyuan county show some characteristics same as other race expect its owe catacteristics different from that.
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